Projects

Medical Image Registration

Image registration is one of today‘s challenging image processing problems. The objective is to find a geometrical transformation that aligns points in one view of an object with corresponding points in another view of the same object or a similar one. Particularly in medical imaging, there are many instances that demand for registration. Typical examples include the treatment verification of pre- and post-intervention images, study of temporal series of images, and the monitoring of time evolution of an agent injection subject to a patient-motion. Another important area is the need for combining information from multiple images acquired using different modalities, sometimes also called fusion.

In summary, image registration is inevitable whenever images acquired from different subjects, at different times, or from different scanners need to be combined or compared for analysis or visualization.

The focus of this project is the development of algorithms which are capable of dealing with high-resolution, high dimensional, and/or time critical applications. Examples include the registration of histological slices of a human brain (here, each of the 6.000 slices has a resolution of about 10.000 x 20.000 pixel), the registration of a time series of three-dimensional MRI’s, the online correction of the so-called brain shift during the surgery, or the registration of diffusion tensor images (DTI‘s).

Contact

Bernd Fischer
Institute of Mathematics,
University of Lübeck
Phone: ++49-451-7030-434
E-Mail: fischer@math.uni-luebeck.de

Jan Modersitzki
Institute of Mathematics,
University of Lübeck
Phone: ++49-451-7030-434
E-Mail: modersitzki@math.uni-luebeck.de